Below is an example of my layout process on a current page. I rough in my layout pages in a combination of pen and the same white gouache I use to do corrections and white hatching/grey tones on my finals.
For this page I printed a light grey of the rough layout onto another sheet of bristol to refine it before going to finish.
For personal projects (where I am exploring a concept and I do not have a clear destination), I sometimes forgo this process. In the example below, the only transfer is the grid that divides the page into fourths and title. The title was initially hand lettered on another illustration, and transferred in blue to the below sheet of bristol.